Introduction: Diabetes mellitus is characterized by altered blood glucose levels; a growing worldwide problem. Management of type II diabetes mellitus involves dietary modifications, physical activity adjustments, pharmacotherapy, herbal therapy, and insulin. Products developed from natural sources is gaining great importance; many natural products have been developed from different parts of plants for curing diabetes mellitus. This study aimed to determine the effect of Morus alba leaf powder on the blood sugar levels of Patients with Type II Diabetes Mellitus.

Methods: It was a randomized control trial; eighty patients diagnosed with type II diabetes mellitus were randomly collected from Fatima Memorial Hospital and were further equally divided into two groups i.e., control group and the experimental group. Control group participants consumed their regular hypoglycemic medications, and participants in the experimental group consumed 500mg Morus alba leaf tablet twice a day, 15 minutes before breakfast and dinner, along with their regular hypoglycemic medications. The total duration of the study was 90 days, divided into four equal visits starting from the baseline measurements to the final measurements.

Results: Fasting blood glucose levels of participants in the control group ranged from 151mg/dl to 146mg/dl, and fasting blood glucose levels of participants in the experimental group ranged from 190mg/dl to 136mg/dl. Conclusion: Results of the study concluded that Morus alba leaves possess efficacy against fasting high blood sugar levels.