In the rural localities of the region of Chernihiv Polesie (Ukraine) there are 86 respondents from 500 interviewed in 2019-2021 residents (including 129 patients with type 2 diabetes) only medicinal plants of the local flora for the diabetes treatment. According to the results of the survey, it was established that in these 86 respondents, the glycated hemoglobin index decreased by 10.8– 26.4% within 1.5–4 years after the initial detection of type 2 diabetes. The plants of local and introduced flora used by respondents for the treatment of diabetes are: Vaccinium myrtillus (92% of respondents), Phaseolus vulgaris (72%), Fragaria vesca (63%), Morus alba (46.5%), Juglans regia (44%), Malus sylvestris (37%), Sambucus nigra (30%), Urtica dioica (27%), Cichorium intybus (24%), Arctium lappa (21%), Robinia pseudoacacia (10.5%).