Diabetes mellitus (DM) is an important health problem that induces microvascular complication such as retinopathy, nephropathy, and neuropathy. Ocular complications associated with type 2 DM are progressive and rapidly becoming the world’s most significant cause of morbidity and preventable with early detection and timely treatment. A prospective, analytical observational with cross-sectional study aimed to analyze of glycemic control and low-density lipoprotein cholesterol (LDL-C) with glaucomatous optic neuropathy as a microvascular complication in patients with type 2 DM, was conducted in Universitas Sumatera Utara Hospital and Satellite Hospital, Medan, Indonesia, from April 2020 to August 2020. The study included 66 participants with type 2 DM. The patients were investigated for hemoglobin A1c (HbA1c) level, LDL-C level, and ophthalmology examination including visual acuity (VA), intraocular pressure (IOP) measurement by Goldmann Applanation Tonometer, retinal nerve fiber layer (RNFL) thickness with spectral domain Optovue optical coherence tomography, and visual field defect with Octopus Perimeter. This study showed a significant correlation between HbA1c with VA (p = 0.030), IOP (p = 0.035), RNFL thickness (p = 0.002), visual field defect (p = 0.032), and duration of DM (p = 0.003) and showed significant correlation between LDL-C with VA (p = 0.048), IOP (p = 0.006), and duration of DM (p = 0.042). This study concluded that higher HbA1c and LDL-C was correlated with Glaucomatous Optic Neuropathy as a microvascular complication in type 2 DM. Collaboration between endocrine and ophthalmology department was strongly advised.

Professor Masitha Dewi Sari is Head of the Ophthalmology Department and Lecturer in the Glaucoma Subdivision in the Ophthalmology Department, Faculty of Medicine, Universitas Sumatera Utara. Professor Dewi finished her Medical Doctor at Universitas Sumatera Utara in 2000 and the Ophthalmology Program at Universitas Sumatera Utara in 2005. Professor Dewi had a Glaucoma Fellowship at the Singapore National Eye Center in 2011. Professor Dewi finished her Master's in Clinical Medicine at Universitas Sumatera Utara in 2012, and her Doctoral Program in 2013. Professor Dewi has published reputable publications and received a lot of interest, especially in her study about glaucoma in Diabetes Patients. Aside from academic, Professor Dewi is an active member in various national and international organizations.