Paola Duchi Jimbo
Endocrinology/ Fellowship in thyroid diseases, EcuadorTitle: Involvement of the thyroid gland secondary to sars cov 2 infection (covid 19) in the general hospital of mexico ´´dr. eduardo liceaga´´ period 2020 - 2021
Abstract
Research Type: Analytical - Cross-sectional
retrospective, Observational.
Context: The current coronavirus pandemic began
on December 8, 2019 in the country of the city of
Wuhan in China with the unusual presentation of
several patients with severe pneumonia of
unidentified cause until that time. On February 11,
2020, the World Health Organization gave the
name COVID-19 to the disease caused by SARSCoV-2 and finally declared it a global pandemic on
March 11, 2020. Coronavirus disease compromises
all organs and biological systems, either by direct
involvement of specific tissues or by indirect
effects. The endocrine system is no exception and
altered thyroid function and parenchyma have been
reported. Histopathological study on the effects of
SARS-CoV - 2 infection in the thyroid showed an
extensive lesion of the para-follicular cells and the
destruction and exfoliation of the epithelial cells in
the thyroid follicle, an interesting finding was the
absence of inflammatory infiltrate which supported
the hypothesis of extensive apoptosis responsible
for the findings In the course of the Covid 19
pandemic, sequelae and affectation of systems
have been observed, having health problems, for
which it has been considered necessary to study the
signs and symptoms related to the thyroid gland
and Covid 19, this has been evidenced with the
increase in cases. of Covid 19 in some cases has
been unnoticed, others symptomatic and even
overcome the severity producing and affecting the
thyroid gland.
General Goal: To determine the relationship
between the degree of severity of the Sars – CoV-2
infection and the involvement of the thyroid Gland.
Specific goal: Demographically characterize the
study patients. To identify the degree of severity
due to Sars – CoV-2 infection in the study patients.
Define the specific diagnosis of thyroid gland
involvement in the study patients. Establish the
relationship between the severity of the Sars-CoV-2 infection and the specific diagnosis of thyroid
gland involvement.
Methodology: A study was carried out at the
General Hospital of Mexico ¨Dr. Eduardo Liceaga¨
in the period 2020 - 2021 with alteration of thyroid
dysfunction the course of the Sars - CoV - 2
disease; Of which 9 presented symptoms of
hypothyroidism and 3 of hyperthyroidism, the
laboratory results confirmed the diagnosis
described. A descriptive and retrospective cross-sectional observational study was carried out, the
information data was collected from the clinical
history of the admitted patients to present them in
a summarized way in tables and graphs with
absolute number and percentage.
Results: One of the concerns in the face of the
COVID-19 pandemic is whether the virus itself can
cause alterations in thyroid function and whether
thyroid diseases increase the infection and the severity of complications. In the present
study, patients admitted to the General Hospital of
Mexico ¨Dr. Eduardo Liceaga¨ with a clinical
picture of severe acute respiratory syndrome
(SARS-CoV-2), without a previous history of
thyroid disease, were investigated. Thyroid
dysfunction in this entity is characterized by phases
of thyrotoxicosis, hypothyroidism and
euthyroidism, each phase is accompanied by the
typical symptoms of thyroid alteration and
characteristic laboratory findings; assessment of
thyroid autoimmunity, which may be undetectable
or present in low titers. A possibility of a
correlation between thyroid disorders, pulmonary
dysfunction and cardiovascular risk has been
raised, with an impact on processes such as
dyspnea, pleural effusion, sleep apnea and other
conditions that favor greater cardiorespiratory
pathophysiological compromise.
Conclusions: In the General Hospital of Mexico
¨Dr. Eduardo Liceaga¨
, due to the great demand for
admissions in the pandemic, cases of Covid 19 and
involvement of the thyroid gland have been
repo
Biography
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