BACKGROUND: There are several treatments for losing weight and sustain it. Food intake is controlled by the neurobehavioral pathway influenced by several factors including persistent behavioral patterns. OBJECTIVE: To evaluate the effect of transcranial direct current stimulation in obese patients undergoing different nutritional therapies. MATERIALS AND METHODS: A clinical, control, double-blind study was done from January 2017 to December 2018 including three groups of patients: one undergoing a protein diet and the other two on a hypocaloric diet. One hypocaloric diet group and the protein diet group were subjected to the transcranial direct current stimulation protocol. The other group received only simulated administration of transcranial direct current stimulation. RESULTS: Patients submitted to the protein diet and transcranial direct current stimulation showed a faster loss of weight than the other 2 groups. Patients undergoing the transcranial direct current stimulation protocol, regardless the diet, showed the greatest change in neural circuits. CONCLUSIONS: Nutritional therapy combined with transcranial direct current stimulation for the treatment of obesity has satisfactory results that impact on the regulation of neural circuits involved with eating behavior, resulting in a greater loss of weight, a better emotional control and cognitive development. 

Eva María Perusquía Frías is a physician graduated with honors from La Salle University in México City. She has a specialty in Internal Medicine from Hospital Español de México in México city with private clinical and hospital practice for 22 years. Also, she has a master’s degree in Humanitarian Sciences from Universidad Anáhuac Querétaro. For 12 years, she has been a mid-time professor in the Medicine Faculty of the Universidad Autónoma de Querétaro in the physiology and nephrology courses. Former president of the Internal Medicine College of Querétaro from 2014 to 2017 and current treasurer. Fellow of the American College of Physicians and Meetings Committee member of the American College of Physicians chapter México. Medical Advisor for the Neurosciences Unit in México city. Physician researcher in Clínica de Salud del Valle de Salinas, California, and currently Internal Medicine provider as part of the Pilot Mexican AB 1045 project. National and International lecturer in more than 65 seminars and meetings.  Member of the Internal Medicine College México and Sociedad Latinoamericana de Medicina Interna (SOLAMI).