
Carlos Danilo Cardoso Matos Silva
Unidade de Ensino Superior de Feira de Santana, BrazilTitle: Physiological changes in glucose uptake by GLUT-4 in Gestational Diabetes Mellitus
Abstract
This study
aimed to identify the physiological changes that occur in the GLUT4 in glucose
uptake in patients with gestational diabetes mellitus, which changes have resulted
due to the increase of counterregulatory hormones
insulin at physiological stress imposed by pregnancy
and by predetermining factors that can be genetic and / or environmental
factors, inflammatory mediators and insulin
resistance. Given that all these metabolic changes interfere directly or
indirectly in glucose uptake by GLUT-4, there was a literature review with
descriptive, explanatory and qualitative approach about the changes suffered
by this carrier in gestational diabetes mellitus. It is therefore concluded that metabolic
changes suffered in DMG interfere directly in the expression and translocation
of the GLUT-4 glucose transporter. Keywords: Metabolism; Gestational diabetes;
Receivers; Insulin resistance.
Biography
To be added