Track: Steroid Hormones and Receptors

Session Overview

Biosynthesis and Classification of Steroid Hormones: Steroid hormones are synthesized from cholesterol primarily in the adrenal glands and gonads. They are classified into glucocorticoids, mineralocorticoids, sex steroids, and vitamin D derivatives. Each class has distinct physiological functions and regulatory mechanisms.

Steroid Hormone Receptors and Signal Transduction: Steroid hormones act through specific intracellular receptors that regulate gene transcription. Hormone–receptor binding initiates signaling pathways that influence cell growth, metabolism, and immune responses. These mechanisms allow precise control of hormonal effects.

Physiological Roles of Steroid Hormones: Steroid hormones regulate essential functions including stress response, electrolyte balance, sexual development, and reproduction. They also play key roles in metabolism, inflammation, and immune modulation. Balanced hormone levels are critical for maintaining homeostasis.

Disorders of Steroid Hormone Excess and Deficiency:Imbalances in steroid hormone production can lead to conditions such as Cushing’s syndrome, Addison’s disease, and congenital adrenal hyperplasia. These disorders affect multiple organ systems and metabolic processes. Early diagnosis supports effective treatment and complication prevention.

Therapeutic Applications and Receptor-Targeted Treatments: Steroid hormones and receptor modulators are widely used in treating inflammatory, autoimmune, and endocrine disorders. Targeted therapies aim to maximize therapeutic benefits while minimizing side effects. Advances in receptor-specific treatments continue to improve clinical outcomes.

6th Global Meeting on Diabetes and Endocrinology

Track: Steroid Hormones and Receptors

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