Track: Stem Cell treatment in Diabetes

Types of Stem Cells Used in Diabetes Therapy

Various stem cells, including embryonic stem cells, induced pluripotent stem cells, and mesenchymal stem cells, are being studied for diabetes treatment. Each type has unique properties related to differentiation and immune response. Their selection depends on therapeutic goals and safety considerations.

Beta-Cell Regeneration and Replacement Strategies

Stem cell–based approaches aim to restore insulin production by regenerating or replacing damaged pancreatic beta cells. These strategies focus on improving cell survival, function, and glucose responsiveness. Successful beta-cell replacement could reduce or eliminate insulin dependence.

Immunomodulation and Autoimmune Control

In type 1 diabetes, immune-mediated destruction of beta cells remains a major challenge. Stem cells may help regulate immune responses and reduce inflammation. Immunomodulatory effects support protection of newly formed or transplanted beta cells.

Clinical Trials and Translational Research

Clinical studies are evaluating the safety and effectiveness of stem cell therapies in diabetes. Translational research bridges laboratory findings with clinical application. These trials help determine optimal delivery methods, dosing, and long-term outcomes.

Ethical, Safety, and Regulatory Considerations

Stem cell therapy raises important ethical and regulatory questions. Ensuring patient safety, preventing tumor formation, and meeting regulatory standards are essential. Clear guidelines and long-term monitoring are required for clinical implementation.

6th Global Meeting on Diabetes and Endocrinology

Track: Stem Cell treatment in Diabetes

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