Infantile hemangiomas are the most common benign vascular tumors in infancy. Their incidence is between 3-10%. They are more frequently observed in females, in preterm babies and in case of perinatal stress. Most of the infantile hemangiomas are benign and do not need systemic treatment, only 12-15% need an oral treatment with Propranolol. The invention of their treatment with oral Propranolol makes a huge revolution in their course. The accurate diagnosis and early treatment are very important for a child prognosis and hemangioma evolution. The treatment must be started in the stage of hemangioma progression in order to have a good final response. The treatment can be started in out- patient or in- patient option with good clinical effect and results. Patients must be prepared with laboratory investigations, dermatology and cardiology consultation. The dose is carefully increased from 1mg/kg to 2 mg/kg and 3 mg/kg/day in a week interval. The dose of 3 mg/kg is the therapeutic dose. We present our experience in management and treatment of infantile hemangiomas. In our clinic as an out – patients twenty patients are observed. Our results demonstrate very satisfied results in the involution of treated patients.